Published: Fri, December 07, 2018
Health Care | By Cedric Leonard

First baby is born using transplanted womb from dead woman

First baby is born using transplanted womb from dead woman

The organ was transplanted into a 32-year-old woman who had a disorder that left her without a uterus.

To date, 39 womb transplants from live donors have been performed, resulting in the birth of 11 babies, according to BBC News.

The surgical team had to connect the donor's uterus with the veins, arteries, ligaments, and vaginal canal of the recipient. In another breakthrough, a team of doctors in Brazil has announced the first birth via a uterus donated from a dead woman.

The woman received the transplant in 2016 from a 45-year-old woman who had three children and died of a stroke.

However, he cautioned: "Uterine transplantation is a novel technique and should be regarded as experimental".

In the Brazilian case, the journal said the recipient had been born without a uterus due to a condition called Mayer-Rokitansky-Küster-Hauser syndrome.

Uterus transplantation was pioneered by Swedish doctor Mats Brannstrom, who has delivered eight children from women who got wombs from family members or friends.

The woman's eggs were fertilised before the operation and were implanted only seven months after the transplant.

A baby has been born to a mother who had a uterus transplant from a deceased owner for the first time.

"The Brazilian group has proven that using deceased donors is a viable option", said the clinic's Dr. Tommaso Falcone, who was involved in the OH case.

"The use of deceased donors could greatly broaden access to this treatment", Dr. Dani Ejzenberg, who led the research, said in a statement.

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Earlier this week, PM Khan had told a group of media persons that he could change the portfolio of ministers who won't perform. Asked why he "harboured anti-US sentiments", Khan said disagreeing with Washington's policies did not make him "anti-American".

After surgery, the anonymous recipient remained in intensive care for two days before spending another six days on a specialised transplant ward.

The girl born in the Brazilian case was delivered via caesarean section at 35 weeks and three days, and weighed 2,550 grams, the case study said.

Canadian Fertility and Andrology Society president Clifford Librach said the challenges of transplant surgery, the need for immunosuppressing drugs to stop organ rejection that could affect the fetus, and other potential risks are big factors that will likely keep this surgery from becoming commonplace.

Research has since continued, with informed volunteers still opting to go through the discomfort and potential trauma in the hopes of giving birth.

Likewise, the mother's health required months of ongoing monitoring to ensure that she didn't suffer any adverse effects from having the uterus transplanted and then later removed.

The woman's pregnancy was normal, and doctors performed a Caesarean section on December 15, 2017, after about 36 weeks (a full term is about 40 weeks).

The authors of The Lancet paper note that uterus transplants involve major surgery and high doses of immunosuppression drugs, and recipients need to be healthy to avoid complications during or after the procedure. Non-invasive prenatal testing was done at 10 weeks, showing a normal foetus, and ultrasound scans at 12 and 20 weeks revealed no fetal anomalies.

The woman was given immunosuppressants to prevent rejection of the womb, while the team took biopsies of the cervix at regular intervals to check for signs of rejection.

It's still early days, but so far, there are no complaints. The immunosuppressive therapy was suspended at the end of the hysterectomy.

In 2016, doctors at the Cleveland Clinic in OH transplanted a uterus from a deceased donor, but it failed after an infection developed.

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